AKT2 Antikörper

Produktnummer ABIN3029475

Dieses Anti-AKT2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von AKT2 in WB, IHC, ELISA und IF. Geeignet für Human und Maus.

Kurzübersicht für AKT2 Antikörper (ABIN3029475)

Target: AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser AKT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Klon: 148CT5-4-1-4

Produktdetails anti-AKT2 Antikörper

Aufreinigung: Purified

Immunogen: This anti-AKT2 antibody was produced from a mouse immunized with AKT2 recombinant protein.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Titration of the anti-AKT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:500,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the anti-AKT2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu AKT2

Target: AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))

Andere Bezeichnung: AKT2

Hintergrund: AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

UniProt: P31751

Pathways: PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, TLR Signalweg, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Hepatitis C, VEGF Signaling